비만 연관 당뇨 및 암 질환의 분자 기전을 밝히고 치료제 개발을 위한 연구를 진행하고 있습니다.
1. 세포외 기질단백질에 의한 지방조직 리모델링 연구
2. 지방조직 분비체 기반 대사성 질환 치료제 개발 연구
3. 종양미세환경에서 지방세포와 암세포간의 상호신호 전달계 연구
4. 대사스트레스에의한 암세포 대응기전 연구
Our research group is mainly focusing on the adipocyte biology at the level of metabolism and cancer.
Through underlying the molecular mechanisms of obesity-related metabolic diseases, we aim to develop novel therapeutics for the metabolism and cancers. Main research topics are listed in below;
1. Adipose tissue remodeling via modulation of extracellular matrix proteins
2. Development of adipokine-based therapeutics for obesity-related metabolic diseases
3. Underlying the signaling networks between stromal adipocytes and cancer cells within the tumor microenvironment
4. Underlying the molecular mechanisms of metabolic stress-induced alteration of cancer cell behaviors