Synthetic Organic Chemistry


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The major research themes in our laboratory are to develop metal-catalyzed synthetic routes to afford functionalized small molecules and to apply synthetic fine chemicals in rechargeable battery systems. Issues of selectivity, oxidation state changes of transition metal complexes, and efficient formation of C–C and C–X bonds have been the central topics of our synthetic approaches.


organic chemistry, redox chemistry, metal-catalyzed organic synthesis


Research Keywords and Topics

The SYH group’s research centers on selective bond activation & functionalization for molecular complexity. Our research themes include (i) metal-catalyzed selective transformations and/or functionalizations of π-system, (ii) directed or nondirected C–H arylation of (hetero)arenes using hypervalent compounds, and (iii) oxidation-state modulation to access active radical species or to activate inert bonds.

Research Publications

- J. Am. Chem. Soc. 2017, 139, 12121–12124. “Nickel-catalyzed azide–alkyne cycloaddition to access 1,5-disubstituted 1,2,3-triazoles in air and water” Kim, W. G.; Kang, M. E.; Lee, J. B.; Jeon, M. H.; Lee, S.; Lee, J.; Choi, B.; Cal, P. M. S. D.; Kang, S.; Kee, J.-M.; Bernardes, G. J. L.; Rohde, J.-U.; Choe, W.; Hong, S. Y.*

- Angew. Chem., Int. Ed. 2017, 56, 5007–5011. “An annulative synthetic strategy for building triphenylene frameworks via multiple C–H activations” Mathew, B. P. ‡; Yang, H. J.‡; Kim, J.; Lee, J. B.; Kim, Y.-T.; Lee, S.; Lee, C. Y.; Choe, W.; Myung, K.; Park, J.-U.*; Hong, S. Y.**

- Adv. Funct. Mater. 2015, 25, 4859–4866. “Mechanistic studies of transition metal-terephthalate coordination complexes upon electrochemical lithiation and delithiation” Lee, H. H.; Park, Y.; Kim, S. H.; Yeon, S.-H.; Kwak, S. K.; Lee, K. T.*; Hong, S. Y.**