Laboratory for Biomaterials and Translational Medicine

생체 재료 및 중개 의학 연구실

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생체 재료 및 중개 의학 연구실

The lab focuses on utilization of functional nanomaterials in diagnostic and therapeutic platforms and finds governing principles for biomedical materials design. Ultimate goals are starting from these findings and set a cutting-edge foundation of engineering sophisticated “multiscale biomedical material systems” for translational applications. In order to achieve the goals, we emphasize fundamental understandings of how nano-structured materials interact with biological systems. We also investigate the thermodynamic and kinetic basis of physicochemical interactions between synthetic biomedical materials and complex biological systems, with a specific focus on the surface chemistry and interface engineering.

Major research field

Nano-bio materials, Drug delivery systems, Bioimaging, Biosensor, Translational medicine, Tissue regeneration

Desired field of research

Biomaterials, Biodegradable materials, Medical diagnosis, Precision medicine

Research Keywords and Topics

Systems Nano-Bioengineering, Biomedical Materials, Nano-Bio interface, Biosensor, Drug Delivery Systems, Regenerative Medicine, Bioimaging, Surface Chemistry, Molecular Engineering, Gene Therapy

Research Publications

· ACS Nano, Aptamer nanoconstructs crossing human blood-brain barrier discovered via microphysiological system-based SELEX technology (2023)
· Journal of Nanobiotechnology, Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration (2023)
· Nanoscale, Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery (2022)
· Nature Biomedical Engineering, Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy (2018)
· Advanced Materials, Tracking the fate of porous silicon nanoparticles delivering a peptide payload by intrinsic photoluminescence lifetime (2018)

국가과학기술표준분류

  • LC. 보건의료
  • LC03. 의약품·의약품개발
  • LC0309. 약물전달시스템

국가기술지도분류

  • 건강한 생명사회 지향
  • 021400. 생체재료기술

녹색기술분류

  • 고효율화기술
  • 환경보건
  • 441. 유해성물질 모니터링 및 환경정화기술

6T분류

  • BT 분야
  • 보건의료 관련응용
  • 020215. 기능성 바이오소재 기반기술