Biochemical Engineering Lab (BCE Lab)

생물공학연구실

관련기사 바로가기
생물공학연구실

Prof. Park has been studying metabolic engineering of microorganisms and their commercial applications. Major interest lies on the production of 3-hydroxypropionic acid (3-HP), 1, 3-propanediol and lactones from renewable raw materials including glucose, glycerol, acetate, CO, etc. Synthesis pathways for target compounds are designed and built in proper host microorganisms and the microorganisms are tested and further engineered by rational and combinatorial approaches in an iterative manner.

관심분야

Microbial biotechnology, Metabolic engineering, 3-hydroxypropionic acid, Lactones

희망분야

Research Keywords and Topics

• Production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol and glucose
글리세롤 및 포도당을 이용한 3-hydroxypropionic acid와 1,3-hydroxypropanediol 의 생산
• Production of 3-hydroxypropionic acid from CO and/or CO-derived acetate
CO 가스나 CO 유래 아세트산을 이용한 3-hydroxypropionic acid의 생산
• Production of lactones from renewable biomass
재생가능 원료를 이용한 바이오 락톤의 생산

Research Publications
MORE

• BIOTECHNOLOGY ADVANCES / Potential and limitations of Klebsiella pneumonia as a microbial cell factory utilizing glycerol as the carbon source / Kumar, Vinod; Park, Sunghoon / 2018-01
• BIORESOURCE TECHNOLOGY / Metabolic engineering of Klebsiella pneumoniae J2B for co-production of 3-hydroxypropionic acid and 1, 3-propanediol from glycerol : Reduction of acetate and other by-products / Ko, Yeongjoo; Seol, Eunhee; Sundara Sekar, Balaji; Kwon, Seongjin; Lee, Jaehyeon; Park, Sunghoon / 2017-11
• BIOTECHNOLOGY FOR BIOFUELS / Co-production of hydrogen and ethanol by pfkA-deficient Escherichia coli with activated pentose-phosphate pathway : reduction of pyruvate accumulation / Sekar, Balaji Sundara; Seol, Eunhee; Raj, Subramanian Mohan; Park, Sunghoon / 2016-04

Patents

• Novel recombinant E. coli strains and method for producing 3- hydroxypropionic acid using thereof, Sunghoon, Park / Yeonhee, Kim / Mugesh Sankaranarayanan, No.10-2028448 / 2019-09
• Development of 3-hydroxypropionic acid inducible promoter system and construction of biological 3-hydroxypropionic acid production pathway using these promoter system, Sunghoon Park / Shengfang Zhou / Somasundar Ashok / Eunhee Seol / Ainala Satish Kumar, No.PCT/KR2016/006261 / 2016-06

국가과학기술표준분류

  • EC. 화공
  • EC04. 생물화학공정기술
  • EC0402. 대사공학기술

국가기술지도분류

  • 건강한 생명사회 지향
  • 020400. 선도물질 최적화기술

녹색기술분류

  • 고효율화기술
  • 친환경 제조공정 및 소재효율성 향상
  • 352. 제조공정/소재 효율성 향상 기타 기술

6T분류

  • BT 분야
  • 기초/기반기술
  • 020116. 생물공정 기술