Faculty Research Profile
Jeonguk Kweon
학력
• 2019~2024: Ph.D., Department of Chemistry, KAIST (Advisor: Prof. Sukbok Chang)
• 2015~2019: B.S. Department of. Chemistry, Seoul National University
주요 경력
• 2026~present: Assistant Professor, UNIST
• 2025~2026: Postdoctoral Fellow, Department of Chemistry and Biosciences (D-CHAB), ETH Zürich
• 2024~2025: Postdoctoral Fellow, Center for Catalytic Hydrocarbon Functionalization (CCHF), Institute for Basic Science (IBS)
수상/학회/외부활동
• 2025: Young Scientist for Lindau Nobel Laureate Meeting
• 2025~2026: Postdoctoral Fellow for Overseas Research, National Research Foundation of Korea (NRF)
• 2022: Best Teaching Assistant Award
• 2019: Summa Cum Laude, Seoul National University
촉매 및 유기합성 연구실
Laboratory for Catalysis and Organic Synthesis
우리 연구실은 간단하고 쉽게 구할 수 있는 화학 원료를 구조적으로 복잡하고 기능성이 우수한 분자로 전환하는 새로운 유기합성 방법론을 개발합니다. 이를 위해 혁신적인 시약과 촉매 시스템을 설계하고, 실험적 분석과 계산화학적 접근을 바탕으로 반응 메커니즘을 규명함으로써 새로운 합성 원리를 제시하고자 합니다. 특히 지구상에 풍부한 제1주기 전이금속 기반 촉매와 광화학·전기화학적 활성화를 활용한 지속가능한 유기합성 기술 개발에 집중하고 있습니다. 장기적으로는 다양한 분자 빌딩 블록을 정밀하고 자유롭게 조합할 수 있는 모듈형 합성 플랫폼을 구축하여, 복잡한 기능성 분자의 합성을 보다 효율적이고 범용적인 기술로 구현하는 것을 목표로 합니다.
We develop new organic synthesis methods that transform simple, readily available chemical feedstocks into structurally complex and functionally valuable molecules. To achieve this goal, we focus on the design of innovative reagents and catalytic systems, while also pursuing mechanistic studies that combine experimental and computational approaches to elucidate the fundamental principles governing these reactions at the molecular level. In particular, we are interested in sustainable synthetic strategies enabled by catalysts based on earth-abundant 1st-row transition metals, as well as by photochemical and electrochemical activation. In the long term, we aim to establish modular synthetic platforms that allow diverse molecular building blocks to be connected in a precise and programmable manner, ultimately making the synthesis of complex target molecules more intuitive, versatile, and broadly accessible.
연구분야
유기합성 방법론 개발, 유기금속화학, 광·전기촉매화학, 계산화학
Organic synthesis method development, Organometallics, Photo- and electrocatalysis, Computational Chemistry
연구주제
제1주기 전이금속(Fe, Cu, Ni 등) 기반 촉매 반응 개발
광촉매 및 전기촉매 반응 개발
라디칼 기반 다기능화 반응 개발
계산화학 기반 반응 메커니즘 규명
Base metal (Fe, Cu, Ni) catalysis
Photocatalytic & electrocatalytic reaction
Radical-involved multifunctionalization
Computation-assisted reaction mechanism investigation
논문
• ACS Catal. 2025, 15, 18383-18390. "Photocatalytic N-N Cross Coupling to Access N’-Aryl Hydrazides”, Kang, J.†, Kweon, J.†, Kim, D., Hong, S., Chang.S*
• Angew. Chem., Int. Ed. 2025, 64, e202422461. “Catalytic Amino Group Transfer Reactions Mediated by Photoinduced Nitrene Formation from Rhodium-Hydroxamates”, Jung, H.†, Kweon, J.†, Suh, J.-M., Arribas, A., Kim, D., Lim, M.-H.*, Chang, S.*
• Org. Lett. 2025, 26, 11167–11172. “Stereoretentive Decarboxylative Amidation of α,β-Unsaturated Carboxylic Acids to Access Enamides”, Kweon, J., Lee, M., Kim, D., Chang, S.*
• Nat. Commun. 2024, 15, 3788. “Decarboxylative Stereoretentive C–N Coupling by Harnessing Aminating Reagent”, Kweon, J.†, Park, B.†, Kim, D., Chang, S.*
• J. Am. Chem. Soc. 2023, 145, 28251–28263. “A Formal γ-C–H Functionalization of Carboxylic Acids Guided by Iridium Nitrenoids as an Unprecedented Mechanistic Motif”, Pradhan, S.†, Kweon, J.†, Sahoo, M. K., Jung, H., Heo, J., Kim, Y. B., Kim, D., Park, J.-W.*, Chang, S.*
• Science 2023, 381, 525–532. “Mechanistic Snapshots of Rhodium-Catalyzed Acylnitrene Transfer Reactions”, Jung, H., Kweon, J., Suh, J.-M., Lim, M.-H., Kim, D.*, Chang, S.*
• J. Am. Chem. Soc. 2022, 144, 9161–9171. “Photoinduced Transition Metal-Free Chan-Evans-Lam-Type Coupling: Dual Photoexcitation Mode with Halide Anion Effect”, Zhou, Z.†, Kweon, J.†, Jung, H., Kim, D., Seo, S.*, Chang, S.*
• J. Am. Chem. Soc. 2022, 144, 1872–1880. “Access to β-Lactams via Iron-Catalyzed Olefin Oxyamidation Enabled by π-Accepting Phthalocyanine Ligand”, Kweon, J., Kim, D., Kang, S., Chang, S.*
• Angew. Chem., Int. Ed. 2021, 60, 2909–2914. “Highly Robust Iron Catalyst System for C(sp3)–H Amidation Leading to γ-Lactams”, Kweon, J., Chang, S.*
특허
• Chang, S.; Kweon, J.; Park, B.; Kim, D. “Novel Amidation Method of Carboxylic Acid Compounds.” Korean Patent Application No. 10-2024-0022033, filed Feb. 15, 2024.