- * 프린트는 Chrome에 최적화 되어있습니다. print

The human body stands as nature's most intricate organic system. To gain a comprehensive understanding of its integrated physiological functions, it becomes crucial to recreate multi-cellular interactions within tissues and map out the networks of dynamic organ systems in vitro. An innovative solution in this pursuit is the development of 'Organ on a chip,' a microfluidic cell culture device that replicates the microenvironment of living organs. This advancement holds the potential to revolutionize drug development by providing alternatives to animal testing. Our current focus lies in constructing 'organ-on-a-chip' systems that incorporate multiple cell types or organoids, capable of emulating human organs in various physiological states. Additionally, for the advancement of precision medicine, we are actively involved in creating personalized organ models utilizing stem cells as a source. By employing these human in vivo-like organ models, we aim to develop novel approaches for drug screening, targeted drug delivery, and real-time observation of drug reactions. Ultimately, our objective is to develop safe and efficient nanomedicines that specifically target distinct physiological microenvironments, thus paving the way for groundbreaking advancements in the field.
Major research field
Organ-on-a-Chip, Organoid, Microfluidics, Nanotherapeutic, Phage Display
Desired field of research
Personalized Medicine, Stem Cell Engineering
Research Keywords and Topics
- Organ-on-a-Chip, Organoid, BioChip, Nanotherapeutic, Phage Display
Research Publications
MOREACS Nano, Aptamer nanoconstructs crossing human blood-brain barrier discovered via microphysiological system-based SELEX technology, Choi JW, Seo M, Kim K, Kim AR, Lee H, Kim HS, Park CG, Cho SW, Kang JH, Joo J, Park TE (2023)
Biomaterials, Human iPS-derived blood-brain barrier model exhibiting enhanced barrier properties empowered by engineered basement membrane, Choi JW, Yoon J, Kim DS, Park TE (2023)
Acta Biomaterialia, Microphysiological system recapitulating the pathophysiology of adipose tissue in obesity, Yoon H, Seo JK, Park TE (2023)
국가과학기술표준분류
- LA. 생명과학
- LA07. 융합바이오
- LA0701. 바이오칩
국가기술지도분류
- 건강한 생명사회 지향
- 021300. 바이오 칩/센서기술
녹색기술분류
- 녹색기술관련 과제 아님
- 녹색기술관련 과제 아님
- 999. 녹색기술 관련과제 아님
6T분류
- BT 분야
- 보건의료 관련응용
- 020213. 생체조직 재생기술